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Like a subgroup Investigation, PPI-resistant GERD team was divided into two teams: erosive team and nonerosive team. The people suffering from erosive esophagitis (erosive group) were outlined as those who experienced findings of grade A, B, C, or D right before switching to VPZ. The patients struggling from nonerosive esophagitis (nonerosive team) were being described as those that had findings of grade M or N just before switching to VPZ. All clients were administered VPZ 20 mg once daily for Preliminary therapy. After the initial therapy, VPZ was decreased to ten mg as being a maintenance therapy. During the maintenance therapy, if signs worsened, VPZ was yet again amplified to twenty mg.
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